ABSTRACT
Objective To explore the risk factors of 43 patients with severe coronavirus disease 2019 pneumonia(COVID-19) in Hangzhou. Methods The clinical and epidemiological data of COVID-19 confirmed patients during 1 st January 2020 and 20 th March 2020 in Hangzhou were collected.The risk factors of the severe cases were analyzed by univariate and multivariate logistic regression. Results Up to 20 th March 2020,a total of 169 patients were reported in Hangzhou, among which, 43(25.44%) were severe cases.The analysis showed that over 60 years old[χ~2=6.16,P=0.01;OR(95%CI)=3.35(1.29-8.69)],hypertension[χ~2=6.91,P<0.001;OR(95%CI)=3.80(1.40-10.28)],headache as initial onset symptom [χ~2=4.80,P=0.03;OR(95%CI)=3.02(1.12-8.09)] and delayed hospitalization(Z=-2.21,P=0.03) were statistically significant. Conclusions Age over 60 years, hypertension, headache as initial onset symptom are risk factors and delayed hospitalization is influencing factor of severe COVID-19 patients.It is necessary to monitor COVID-19 patients′ condition and take effective treatment timely.